Drugs & Vitamins

Renvela Active Ingredients: Sevelamer carbonate Representative Names: Renvela What are Sevelamer carbonate (Renvela™) tablets? What should I tell my health care provider before I take this medicine? How should this medicine be used? What if I miss a dose? What drug(s) may interact with Sevelamer? What side effects may I notice from receiving Sevelamer? What should I watch for while taking Sevelamer? Where can I keep my medicine? What are Sevelamer carbonate (Renvela™) tablets? (Back to top) SEVELAMER is a polymer. It binds phosphates in the stomach and prevents them from being absorbed into the body. This medicine is used in patients with Chronic Kidney Disease on dialysis to prevent dangerous increases in phosphates. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •difficulty swallowing •bowel obstruction •stomach surgery or disorder •an unusual or allergic reaction to sevelamer, medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should this medicine be used? (Back to top) Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take with meals. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. What drug(s) may interact with Sevelamer? (Back to top) Do not take this medicine with any of the following medications: •phosphorus containing product or supplement This medicine may also interact with the following medications: •ciprofloxacin •medicines for an irregular heartbeat •medicines for seizure control Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving Sevelamer? (Back to top) Side effects that you should report to your doctor or health care professional as soon as possible: •allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue •confusion, irritability •difficulty breathing •fever, infection •new or worsening constipation •unusually weak or tired •vomiting Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): •cough •diarrhea •headache •pain •stomach upset, nausea What should I watch for while taking Sevelamer? (Back to top) Visit your Doctor or health care professional for regular check ups. Follow the diet as directed by your doctor. If you are taking other medications, take them at least 1 hour before or 3 hours after taking this medicine. Where can I keep my medicine? (Back to top) Keep out of the reach of children. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date. Last Updated:11/02/2007 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.